Cells incubated with only secondary antibody served as controls.
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Presented are the mean from 3 to 12 biological replicates each conducted with four technical replicates in which S-protein-driven cell entry was normalized against B.
The Omicron spike mediates entry into cell lines with different efficiency as compared with B.
Further, the high number of mutations in the viral spike protein raised concerns that the virus might evade antibodies induced by infection or vaccination.